Bayesian Co-clustering of Anopheles Gene Expression Time Series: A Study of Immune Defense Responses To Multiple Experimental Chal- lenges
نویسندگان
چکیده
Department of Mathematics, Imperial College London, Huxley Building, 180 Queens Gate, London SW7 2AZ, UK; Oxford Centre for Gene Function, Department of Statistics, University of Oxford, Oxford, UK and MRC Mammalian Genetics Unit, Harwell, Oxford, OX11 0RD, U.K; and Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, 615 N. Wolfe Street, Baltimore, MD21205, USA.
منابع مشابه
Bayesian coclustering of Anopheles gene expression time series: study of immune defense response to multiple experimental challenges.
We present a method for Bayesian model-based hierarchical coclustering of gene expression data and use it to study the temporal transcription responses of an Anopheles gambiae cell line upon challenge with multiple microbial elicitors. The method fits statistical regression models to the gene expression time series for each experiment and performs coclustering on the genes by optimizing a joint...
متن کاملA Bayesian Co-clustering of Anopheles Gene Expression Time Series Responses to Multiple Immune Challenges
Department of Mathematics, Imperial College London, Huxley Building, 180 Queens Gate, London SW7 2AZ, UK; Oxford Centre for Gene Function, Department of Statistics, University of Oxford, Oxford, UK and MRC Mammalian Genetics Unit, Harwell, Oxford, OX11 0RD, U.K; and Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, 615 N. Wolfe Street, Baltimore, MD2120...
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